๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-05-26

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma (NCT06297226)

A Phase 2, Open-Label, Multicenter Study of Arlocabtagene Autoleucel (BMS-986393), a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma (QUINTESSENTIAL)

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate the effectiveness and safety of Arlocabtagene Autoleucel (BMS-986393) in participants with relapsed or refractory multiple myeloma.

Who can join: Review the eligibility criteria below.

Location: University of Alabama at Birmingham โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (52 Sites)

Showing the first 25 of 52 sites.

  • University of Alabama at Birmingham โ€” Birmingham, Alabama
  • Banner MD Anderson Cancer Center โ€” Gilbert, Arizona
  • University of Arkansas for Medical Sciences โ€” Little Rock, Arkansas
  • UCLA Hematology/Oncology - Westwood (Building 200 Suite 214) โ€” Los Angeles, California
  • UCSF Helen Diller Medical Center at Parnassus Heights โ€” San Francisco, California
  • Colorado Blood Cancer Institute โ€” Denver, Colorado
  • Mayo Clinic in Florida โ€” Jacksonville, Florida
  • Miami Cancer Institute at Baptist Health, Inc. โ€” Miami, Florida
  • Moffitt Cancer Center โ€” Tampa, Florida
  • Winship Cancer Institute of Emory University โ€” Atlanta, Georgia
  • Northside Hospital โ€” Atlanta, Georgia
  • Northwestern Memorial Hospital โ€” Chicago, Illinois
  • University of Chicago Medical Center โ€” Chicago, Illinois
  • University of Iowa โ€” Iowa City, Iowa
  • The University of Kansas Cancer Center - Westwood โ€” Westwood, Kansas
  • Norton Women's and Children's Hospital โ€” Louisville, Kentucky
  • Local Institution - 0065 โ€” Baltimore, Maryland
  • Massachusetts General Hospital โ€” Boston, Massachusetts
  • Dana-Farber Cancer Institute โ€” Boston, Massachusetts
  • Mayo Clinic in Rochester, Minnesota โ€” Rochester, Minnesota
  • Washington University School of Medicine โ€” St Louis, Missouri
  • Rutgers Cancer Institute of New Jersey โ€” New Brunswick, New Jersey
  • Roswell Park Cancer Institute โ€” Buffalo, New York
  • Icahn School of Medicine at Mount Sinai โ€” New York, New York
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York

๐Ÿ“ž Contact the Study Coordinator

Phone: (855) 907-3286

Email: Clinical.Trials@bms.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Multiple Myeloma clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—