MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial (NCT06319248)
🩺 Plain-English Summary (8th-Grade Level)
This study is being done to determine if early administration of Midodrine can improve outcomes by maintaining a higher mean blood pressure off of intravenous medications. Researchers want to see if Midodrine can help people with sepsis need fewer vasopressors, which could mean shorter hospital stays, less time with uncomfortable tubes, and a smoother recovery overall.
Who can join: Review the eligibility criteria below.
Location: Mayo Clinic Arizona — Scottsdale, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (5 Sites)
- Mayo Clinic Arizona — Scottsdale, Arizona
- Mayo Clinic Florida — Jacksonville, Florida
- Mayo Clinic Health System - Mankato — Mankato, Minnesota
- Mayo Clinic Minnesota — Rochester, Minnesota
- Mayo Clinic Health System - Eau Claire — Eau Claire, Wisconsin
📞 Contact the Study Coordinator
Phone: (507) 255-0148
Email: Schuchard.Amy@mayo.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Sepsis
- A Multicenter Prospective Observational Study to Derive and Verify the Performance of a Host-response Based Diagnostic Tool for Early Detection of Severe Infections. — New York, New York
- Dynamics of Organ Damage and Immune Exhaustion During Sepsis — Rochester, Minnesota
- PICS: Subtitle Cardiac Dysfunction in Older Sepsis Survivors — Gainesville, Florida
- A Validation Study of the Lab Clasp Device: A Point of Care Sepsis Risk Monitor — Boston, Massachusetts
- A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning — New Haven, Connecticut
- Sepsis Associated Encephalopathy (SAE) Biomarkers — Gainesville, Florida
Explore by condition: All Sepsis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.