Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment. (NCT06323824)
Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment - A Pragmatic Hybrid Effectiveness/Implementation Trial
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this clinical trial is to compare the effectiveness of office-based methadone with pharmacy administration and/or dispensing to office-based buprenorphine for the treatment of opioid use disorder. This study will also examine factors influencing the implementation of office-based methadone.
Who can join: Review the eligibility criteria below.
Location: Highland Hospital Bridge Clinic at Alameda Health System — Oakland, California
Age range: 18 Years to 99 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (6 Sites)
- Highland Hospital Bridge Clinic at Alameda Health System — Oakland, California
- Outpatient Buprenorphine Induction Clinic, University of California, San Francisco — San Francisco, California
- Rapid Start Clinic, Kaiser Permanente Colorado — Denver, Colorado
- Officed Based Addiction Treatment Program, Boston Medical Center — Boston, Massachusetts
- Hennepin Healthcare Addiction Medicine — Minneapolis, Minnesota
- Marshall University Division of Addiction Sciences P.R.O.A.C.T — Huntington, West Virginia
📞 Contact the Study Coordinator
Phone: (203) 785-6821
Email: j.mckenzie@yale.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Opioid Use Disorder
- Therapy and Peer Support for Patients Taking Medication for Opioid Use Disorder — Atlantic City, New Jersey
- The Emergency Department Longitudinal Integrated Care — Seattle, Washington
- Virtual Reality Cognitive-Affective Training for Opioid Use Disorder- A Phase 2 RCT — La Jolla, California
- Extended-release Buprenorphine as a Novel Low-dose Induction Strategy — Boston, Massachusetts
- Healing Opioid Misuse and Pain Through Engagement (HOPE) Trial — Ann Arbor, Michigan
- Telemedicine XR-B for Individuals in Jail — Cumberland, Maryland
Explore by condition: All Opioid Use Disorder clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.