Physiology of Unloading VA ECMO Trial (NCT06336655)
🩺 Plain-English Summary (8th-Grade Level)
The goal of this clinical trial is to compare the use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) with and without left ventricular (LV) unloading in patients being treated for cardiogenic shock (CS). The main aims of the study are: 1. To determine the physiologic effects on cardiopulmonary congestion of adding LV unloading to VA ECMO 2. To determine the effects on myocardial function of adding LV unloading to ECMO 3. To test the effects on myocardial recovery of adding LV unloading to VA ECMO Participants who are being treated with VA ECMO will be randomized to receive or not receive LV unloading in the form of an intra-aortic balloon pump (IABP). Over the course of the study, the investigators will obtain measurements via lab work, echocardiography, and pulmonary artery catheter that will allow comparison of the two groups.
Who can join: Review the eligibility criteria below.
Location: University of Utah — Salt Lake City, Utah
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Utah — Salt Lake City, Utah
📞 Contact the Study Coordinator
Phone: (801) 587-9373
Email: joseph.tonna@hsc.utah.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cardiogenic Shock
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- Augmented Pacing for Shock in the Cardiac Intensive Care Unit — Nashville, Tennessee
- Can Escalation Reduce Acute Myocardial Infarction Mortality in Cardiogenic Shock — Loma Linda, California
- CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock — Boston, Massachusetts
- Intra-aortic Balloon Counterpulsation (IABC) Compliance — Philadelphia, Pennsylvania
- Hemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock Trial — Falls Church, Virginia
Explore by condition: All Cardiogenic Shock clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.