A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants (NCT06345339)
A Phase 2/3 Multicenter, Double Blinded, Randomized, Dose-conversion, Active Control Study Examining the Efficacy and Safety of Armour Thyroid Compared to Synthetic T4 for the Treatment of Adults With Primary Hypothyroidism
🩺 Plain-English Summary (8th-Grade Level)
This study will evaluate the efficacy and safety of Armour Thyroid treatment compared with synthetic T4 in subjects who have primary hypothyroidism and are currently stabilized (i.e., in-range thyroid-stimulating hormone \[TSH\]) on synthetic T4 treatment. This study will also therefore evaluate the efficacy and safety of dose conversion from synthetic T4 therapy to Armour Thyroid therapy.
Who can join: Review the eligibility criteria below.
Location: Central Research Associates /ID# 255719 — Birmingham, Alabama
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (139 Sites)
Showing the first 25 of 139 sites.
- Central Research Associates /ID# 255719 — Birmingham, Alabama
- UAB Hospital /ID# 262565 — Birmingham, Alabama
- Kaiser San Diego Dept Endocrinology, SCPMG /ID# 262552 — Bonita, California
- Facey Medical Foundation - Burbank /ID# 262104 — Burbank, California
- John Muir Medical Center /ID# 257103 — Concord, California
- Diagnamics Inc. /ID# 262680 — Encinitas, California
- Providence - St. Jude Medical Center /ID# 256520 — Fullerton, California
- NorCal Medical Research /ID# 256512 — Greenbrae, California
- Velocity Clinical Research - Huntington Park /ID# 259044 — Huntington Park, California
- Scripps Whittier Diabetes Institute /ID# 259215 — La Jolla, California
- Facey Medical Foundation /ID# 260863 — Mission Hills, California
- Hoag Memorial Hospital Presbyterian /ID# 260990 — Newport Beach, California
- Diabetes Associates Medical Group /ID# 256949 — Orange, California
- Western University of Health Sciences /ID# 262183 — Pomona, California
- Research at Mills-Peninsula Medical Center - Sutter Health /ID# 258825 — San Mateo, California
- Care Access - Santa Clarita /ID# 262573 — Santa Clarita, California
- Facey Medical Foundation - Valencia /ID# 262102 — Santa Clarita, California
- Olive View UCLA Medical Center /ID# 259092 — Sylmar, California
- The Lundquist Institute at Harbor-UCLA Medical Center /ID# 262572 — Torrance, California
- Diablo Clinical Research /ID# 261329 — Walnut Creek, California
- San Fernando Valley Health Institute /ID# 257363 — West Hills, California
- New England Research Associates - Bridgeport /ID# 262184 — Bridgeport, Connecticut
- Innovative Research of West Florida /ID# 257356 — Clearwater, Florida
- ALL Medical Research /ID# 256748 — Cooper City, Florida
- Northeast Research Institute (NERI) /ID# 261841 — Fleming Island, Florida
📞 Contact the Study Coordinator
Phone: (844) 663-3742
Email: abbvieclinicaltrials@abbvie.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Hypothyroidism
- Gluten Free Diet in Hashimoto's Hypothyroidism — Cleveland, Ohio
- Discontinuation of Low-Dose Levothyroxine in Older Adults With Subclinical Hypothyroidism — Little Rock, Arkansas
- An Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of North Star Desiccated Porcine Thyroid Extract Tablets. — Modesto, California
- Dosing of LT4 in Older Individuals — Philadelphia, Pennsylvania
- Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing — San Francisco, California
Explore by condition: All Hypothyroidism clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.