๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-01-13

Neoadjuvant INBRX-106 in Combination With Pembrolizumab for Stage II/III TNBC Patients (NCT06353997)

A Phase II, Single-arm, Multi-center, Open-label Study of Neoadjuvant INBRX-106 (Hexavalent OX40 Agonist) in Combination With Pembrolizumab as an Induction Immunotherapy for Stage II/III TNBC Patients

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Providence Health & Services

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a Phase II trial to assess efficacy and feasibility of pembrolizumab + INBRX-106 as an induction therapy preceding neoadjuvant therapy.

Who can join: Review the eligibility criteria below.

Location: Ellison Institute of Technology (EITM) โ€” Los Angeles, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (4 Sites)

  • Ellison Institute of Technology (EITM) โ€” Los Angeles, California
  • Providence Portland Cancer Institute - Franz Clinic โ€” Portland, Oregon
  • Providence St. Vincent Medical Center โ€” Portland, Oregon
  • Swedish Cancer Institute โ€” Seattle, Washington

๐Ÿ“ž Contact the Study Coordinator

Phone: (503) 215-1979

Email: canrsrchstudies@providence.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—