A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy (NCT06388707)
A Prospective, Open-label, Single-arm, Multi-center, Pilot Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Unilateral or Bilateral Temporal Lobe Epilepsy
🩺 Plain-English Summary (8th-Grade Level)
This will be a prospective, open-label, single-arm, multi-center, pilot study to evaluate the safety, tolerability, and preliminary efficacy of low-intensity focused ultrasound (LIFU) neuromodulation using NaviFUS System in patients with drug-resistant unilateral or bilateral temporal lobe epilepsy (DR-TLE).
Who can join: Review the eligibility criteria below.
Location: Stanford University School of Medicine — Palo Alto, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- Stanford University School of Medicine — Palo Alto, California
- Brigham and Women's Hospital — Boston, Massachusetts
- University of Virginia School of Medicine — Charlottesville, Virginia
📞 Contact the Study Coordinator
Phone: (022) 586-0560
Email: stfung@navifus.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Drug Resistant Epilepsy
- The Efficacy of a Subanesthetic Doses of IV Ketamine in the Treatment Drug Resistant Epilepsy — New York, New York
- Low Intensity Focused Ultrasound Epilepsy: A Pilot Trial — Boston, Massachusetts
- Goals for Epilepsy Clinic Visits Trial — Ann Arbor, Michigan
- Infrared Photobiomodulation in Humans With Epilepsy — Boston, Massachusetts
Explore by condition: All Drug Resistant Epilepsy clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.