A Study of LY4170156 in Participants With Selected Advanced Solid Tumors (NCT06400472)
A First-in-Human, Phase 1a/1b Trial to Assess the Safety, Tolerability and Preliminary Efficacy of LY4170156, an Antibody-Drug Conjugate Targeting Folate Receptor ฮฑ-Expressing Tumor Cells, in Participants With Selected Advanced Solid Tumors
๐ฉบ Plain-English Summary (8th-Grade Level)
The purpose of this study is to find out whether the study drug, LY4170156, is safe, tolerable and effective in participants with advanced solid tumors. The study is conducted in two parts - phase Ia (dose-escalation, dose-optimization) and phase Ib (dose-expansion). The study will last up to approximately 4 years.
Who can join: Review the eligibility criteria below.
Location: HonorHealth โ Scottsdale, Arizona
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (23 Sites)
- HonorHealth โ Scottsdale, Arizona
- University of California, San Diego (UCSD) - Moores Cancer Center โ La Jolla, California
- South Texas Accelerated Research Therapeutics (START) Midwest โ Grand Rapids, Michigan
- NYU Langone Health - Long Island โ Mineola, New York
- New York University (NYU) Clinical Cancer Center โ New York, New York
- David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center โ New York, New York
- The Ohio State University (OSU) Wexner Medical Center โ Columbus, Ohio
- The University of Texas - MD Anderson Cancer Center โ Houston, Texas
- START Mountain Region โ West Valley City, Utah
- Cancer Research SA โ Adelaide,
- Icon Cancer Centre South Brisbane โ QLD,
- Centre Leon Berard โ Lyon,
- Institut de Cancerologie de l'Ouest - site St-Herblain โ Saint-Herblain,
- Oncopole Claudius Regaud โ Toulouse,
- Humanitas San Pio X โ Milan,
- Istituto Europeo di Oncologia โ Milan,
- Shizuoka Cancer Center โ Shizuoka,
- National Cancer Center Hospital โ Tokyo,
- Cancer Institute Hospital of JFCR โ Tokyo,
- National Cancer Center โ Goyang-si Gyeonggi-do,
- Hospital Universitario Vall d'Hebron โ Barcelona,
- Hospital Universitario 12 de Octubre โ Madrid,
- Hospital Clinico Universitario de Valencia โ Valencia,
๐ Contact the Study Coordinator
Phone: (317) 615-4559
Email: LillyTrials@Lilly.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.