An Innovative Master Platform for Clinical Trials in Mood Disorders (NCT06408012)
Enabling Neuroscience Research Approaches for Brain, feeLings and Emotions (ENABLE): An Innovative Platform for Clinical Trials in Mood Disorders
🩺 Plain-English Summary (8th-Grade Level)
Mood disorders such as depression and bipolar disorder affect over 350 million people around the world. While several effective treatments exist, it is often difficult to match the right treatment to an individual person. Repeated efforts to find the right treatment contribute to poor functioning, low quality of life, and prolongs the time it takes to get well. Most areas of medicine are able to use 'biomarkers' or clinical tests, blood tests, or imaging to help diagnose and treat illness. The search for biomarkers in mood disorders is advancing, but one roadblock to progress is the lack of large, standardized studies of mood disorders that are needed to accurately identify biomarkers. The aim of the ENABLE platform is to provide the Canadian neuroscience community a standardized way of collecting biomarker data from individuals with a range of mood disorders symptoms. In addition, this 'master clinical trial platform' framework will provide a pool of participants who can be recruited into biomarker-based clinical trials.
Who can join: Review the eligibility criteria below.
Location: University of Calgary — Calgary, Alberta
Age range: 16 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (9 Sites)
- University of Calgary — Calgary, Alberta
- University of British Columbia — Vancouver, British Columbia
- Nova Scotia Health Authority — Halifax, Nova Scotia
- McMaster University — Hamilton, Ontario
- Queen's University — Kingston, Ontario
- University of Ottawa — Ottawa, Ontario
- University Health Network — Toronto, Ontario
- Centre for Addiction and Mental Health — Toronto, Ontario
- Ontario Shores Centre for Mental Health Sciences — Whitby, Ontario
📞 Contact the Study Coordinator
Phone: (905) 522-1155
Email: skhoshro@stjoes.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Mood Disorders
- Brain, Emotions, and Mind-Wandering — Pittsburgh, Pennsylvania
- Reconnecting to Ourselves and Others in Virtual Meetings (ROOM) — Charlestown, Massachusetts
- Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers — Bethesda, Maryland
- I-CARE: A Pilot Study of Cognitive Behavioural Therapy(CBT) for Mood and Anxiety Disorders — Toronto, Ontario
- RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty — Monroeville, Pennsylvania
- Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders — Bethesda, Maryland
Explore by condition: All Mood Disorders clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.