πŸ›οΈ Verified NIH Record β€’ Updated 2026-02-20

A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial) (NCT06422884)

A Phase 2, Multi-Center, Randomized, Double-Blind, Controlled Trial Evaluating the Safety and Efficacy of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)

πŸ”΅ Active, Not Recruiting Phase2 πŸ’Š Investigational Drug / Biologic Sponsor: Endeavor Biomedicines, Inc.

🩺 Plain-English Summary (8th-Grade Level)

The goal of this clinical trial is to evaluate the impact that ENV-101 has on lung function and key measures of fibrosis in adult patients with idiopathic pulmonary fibrosis (IPF). Another goal of this study is to better understand the safety and tolerability of ENV-101 in this patient population.

Who can join: Review the eligibility criteria below.

Location: Research Site β€” Quilmes, Buenos Aires

Age range: 40 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (78 Sites)

Showing the first 25 of 78 sites.

  • Research Site β€” Quilmes, Buenos Aires
  • Research Site β€” Buenos Aires,
  • Research Site β€” Buenos Aires,
  • Research Site β€” Mendoza,
  • Research Site β€” Mendoza,
  • Research Site β€” Camperdown, New South Wales
  • Research Site β€” Macquarie Park, New South Wales
  • Research Site β€” Brisbane, Queensland
  • Research Site β€” South Brisbane, Queensland
  • Research Site β€” Box Hill, Victoria
  • Research Site β€” Nedlands, Western Australia
  • Research Site β€” Graz, Styria
  • Research Site β€” Vienna,
  • Research Site β€” Dinant, Namur
  • Research Site β€” Brussels,
  • Research Site β€” Brussels,
  • Research Site β€” Edmonton, Alberta
  • Research Site β€” Vancouver, British Columbia
  • Research Site β€” Ajax, Ontario
  • Research Site β€” Montreal, Quebec
  • Research Site β€” Sherbrooke, Quebec
  • Research Site β€” Trois-RiviΓ¨res, Quebec
  • Research Site β€” Angers,
  • Research Site β€” Bordeaux,
  • Research Site β€” Caen,

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—