Impact of Cognitive Behavioral Therapy on PTSD-CVD Link (NCT06429293)
Impact of Cognitive Behavioral Therapy on Neural, Inflammatory, & Autonomic Markers in a Sample With PTSD and Cardiovascular Risk: Protocol for a Pilot Randomized Controlled Trial
🩺 Plain-English Summary (8th-Grade Level)
This is a pilot randomized controlled trial to assess the impact of a first-line treatment for posttraumatic stress disorder (PTSD) (Cognitive Processing Therapy; CPT) versus waitlist control on mechanisms of cardiovascular disease (CVD) risk. Further, this study will test the hypothesis that CPT reduces CVD risk through its effects on inflammation and autonomic function and that these changes are driven by changes in stress-related neural activity (SNA)
Who can join: Review the eligibility criteria below.
Location: Massachusetts General Hospital — Boston, Massachusetts
Age range: 18 Years to 65 Years
🧪 Interventions in This Study
- Cognitive processing therapy (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Massachusetts General Hospital — Boston, Massachusetts
📞 Contact the Study Coordinator
Phone: (617) 726-1843
Email: MOSBORNE@PARTNERS.ORG
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Posttraumatic Stress Disorder
- Predicting Responses to PTSD Treatment With Iris and Cardiovascular Tests — Seattle, Washington
- A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD — Birmingham, Alabama
- Testing a PTSD m-Health Intervention to Improve Alcohol Treatment Outcomes — Grand Rapids, Michigan
- Using Data Science To Center Patient Perspectives in Mechanism Discovery — Malden, Massachusetts
- Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for CPT-Text for PTSD — Palo Alto, California
- Enhancing Week-long Psychological Treatment for PTSD With Ketamine — New Haven, Connecticut
Explore by condition: All Posttraumatic Stress Disorder clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.