Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure (NCT06446453)
🩺 Plain-English Summary (8th-Grade Level)
Point-of-care ultrasound (POCUS) is the use of ultrasound by the bedside provider in real time to answer a specific question and guide medical management. POCUS can be used to diagnose the severity of neonatal respiratory distress syndrome (RDS) through a lung ultrasound score. Lung ultrasound scores have also been shown to predict if an infant is treated with an initial dose of surfactant. Therefore, using lung ultrasound scores to guide surfactant therapy for RDS will likely lead to earlier surfactant therapy and may improve short-term respiratory outcomes. This study will test this theory by comparing lung ultrasound score-guided surfactant therapy for premature infants with RDS with our current surfactant administration guidelines.
Who can join: Review the eligibility criteria below.
Location: Connecticut Children's — Hartford, Connecticut
Age range: 0 Hours to 2 Hours
🧪 Interventions in This Study
- Echography-guided Surfactant THERapy (ESTHER) (DIAGNOSTIC_TEST)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Connecticut Children's — Hartford, Connecticut
📞 Contact the Study Coordinator
Phone: (860) 545-9720
Email: jkelner@connecticutchildrens.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Respiratory Distress Syndrome, Newborn
- Measuring Diaphragm Electrical Activity in Neonates Using a Smaller Inter-electrode Distance — Toronto, Ontario
- Prophylactic Minimally Invasive Surfactant Evaluation — Evanston, Illinois
- Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting — Rochester, Minnesota
- Utilization of Lung Ultrasound Score in Decision for Minimally Invasive Surfactant Administration — Hackensack, New Jersey
Explore by condition: All Respiratory Distress Syndrome, Newborn clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.