Dose Optimization of Caffeine for HIE (NCT06448780)

🧪 Interventions in This Study

• Caffeine citrate 20 mg/kg (DRUG)
• Caffeine citrate 30 mg/kg (DRUG)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (2 Sites)

• The University of North Carolina at Chapel Hill Newborn Critical Care Center — Chapel Hill, North Carolina
• Novant Health New Hanover Regional Medical Center — Wilmington, North Carolina

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Hypoxic-Ischemic Encephalopathy

• Healthy Little Eyes — Madison, Wisconsin
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia — Little Rock, Arkansas
• Evaluating a Wireless NIRS Device in the Neonatal Intensive Care Unit — Montreal, Quebec

Explore by condition: All Hypoxic-Ischemic Encephalopathy clinical trials

💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Review the official NIH record below to find the coordinating site.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.