Cannabidiol After Multi-Trauma for Pain and Opioid Therapy (NCT06448923)
Effects of an Acute 1-month Cannabidiol Treatment on Pain and Inflammation After a Long Bone Fracture: a Triple-blind Randomized, Placebo Controlled Clinical Trial
🩺 Plain-English Summary (8th-Grade Level)
The aim of this project is to investigate the therapeutic potential and safety of acute Cannabidiol (CBD) treatment on longitudinal pain symptoms, and to assess potential interactions with pain mediators including opioids and sex on CBD treatment response. To this end, this research protocol proposes a comprehensive translational approach including a placebo-controlled randomized clinical trial comparing two daily doses of CBD treatment administered for one month on pain relief. This study will also compare intervention conditions on inflammation markers, participant quality of life, sleep quality, depression, anxiety, cognition and orthopaedic function.
Who can join: Review the eligibility criteria below.
Location: Hôpital Sacré-Coeur de Montréal — Montreal, Quebec
Age range: 18 Years to 70 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Hôpital Sacré-Coeur de Montréal — Montreal, Quebec
📞 Contact the Study Coordinator
Phone: (514) 338-2222
Email: louis.de.beaumont@umontreal.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Fracture
- The PREVENT Trial: a Pragmatic Cluster Randomized Controlled Trial of a Multifaceted Fracture Prevention Model for Long-term Care — Hamilton, Ontario
- Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department — Camden, New Jersey
- Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation — Edmonton, Alberta
- Pediatric Orthopaedic Implant Safety & Efficacy — Vancouver, British Columbia
Explore by condition: All Fracture clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.