IMplementation of CAB+RPV LA for People With HIV in Non-Metropolitan Areas (NCT06451341)
IMplementation of CAB+RPV LA for People With HIV in Non-Metropolitan Areas: Addressing Adherence Barriers Through Learning and Evidence-Informed Strategies (IM-CAPABLE)
🩺 Plain-English Summary (8th-Grade Level)
The goal of this implementation science study is to learn about the experience of receiving and providing cabotegravir + rilpivirine long-acting (CAB+RPV LA) injections as treatment for human immunodeficiency virus (HIV) for people who live a significant distance from an HIV provider. The main questions it aims to answer are: * Is CAB+RPV LA feasible and acceptable to patients and staff? * What barriers and supports exist and have the most impact on receiving and providing CAB+RPV LA? * How does CAB+RPV LA affect HIV stigma, treatment satisfaction, medication adherence and viral suppression? People living with HIV who reside outside of the Omaha, Nebraska metro area and are starting CAB+RPV LA as part of regular medical care for HIV will be invited to participate in this study which involves completing questionnaires and an interview over 15 months. Clinic staff who are involved in providing HIV care and CAB+RPV LA will also provide input through questionnaires and interviews.
Who can join: Review the eligibility criteria below.
Location: Myrtue Medical Center — Harlan, Iowa
Age range: 19 Years
🧪 Interventions in This Study
- Acceptability of Intervention Measure (AIM) (BEHAVIORAL)
- Intervention Appropriateness Measure (IAM) (BEHAVIORAL)
- Feasibility of Intervention Measure (FIM) (BEHAVIORAL)
- HIV Stigma Scale Questionnaire (BEHAVIORAL)
- HIV Treatment Satisfaction Questionnaire status version (HIVTSQs12) (BEHAVIORAL)
- HIV Treatment Satisfaction Questionnaire change version (HIVTSQc12) (BEHAVIORAL)
- Needs and Barriers Assessment (BEHAVIORAL)
- Pre-visit Outreach (BEHAVIORAL)
- Qualitative interview - patient participants (BEHAVIORAL)
- Staff education (BEHAVIORAL)
- Staff Month 7 and 15 Survey - Staff Burden and Engagement (BEHAVIORAL)
- Qualitative interview - staff (BEHAVIORAL)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (4 Sites)
- Myrtue Medical Center — Harlan, Iowa
- Shenandoah Medical Center — Shenandoah, Iowa
- Nebraska Medicine Grand Island Clinic — Grand Island, Nebraska
- University of Nebraska Specialty Care Center — Omaha, Nebraska
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.