🏛️ Verified NIH Record • Updated 2026-03-30

A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis (NCT06454188)

A Randomized, Placebo-controlled, Multicenter, Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis (UP-SPOUT)

🟢 Recruiting Phase4 💊 Investigational Drug / Biologic Sponsor: CARE ARTHRITIS LTD.

🩺 Plain-English Summary (8th-Grade Level)

A Randomized, Placebo-controlled, Multicenter, Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients with Active Psoriatic Arthritis (UP-SPOUT)

Who can join: Review the eligibility criteria below.

Location: University Hospitals Cleveland Medical Center — Cleveland, Ohio

Age range: 18 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (5 Sites)

  • University Hospitals Cleveland Medical Center — Cleveland, Ohio
  • Oregon Health and Science University — Portland, Oregon
  • University of Pennsylvania — Philadelphia, Pennsylvania
  • The Ottawa Hospital Research Institute — Ottawa, Ontario
  • Groupe de Recherche en Maladies Osseuses (G.R.M.O.) Inc. — Québec, Quebec

📞 Contact the Study Coordinator

Phone: (587) 400-9524

Email: amanda.carapellucci@carearthritis.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗