A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence (NCT06492616)
Elacestrant Versus Standard Endocrine Therapy in Women and Men With Node-positive, Estrogen Receptor-positive, HER2-negative, Early Breast Cancer With High Risk of Recurrence-A Global, Multicenter, Randomized, Open-label Phase 3 Study
🩺 Plain-English Summary (8th-Grade Level)
The primary goal of this study is to evaluate the effectiveness of elacestrant versus standard endocrine therapy in participants with node-positive, Estrogen Receptor-positive (ER+), Human Epidermal Growth Factor-2 negative (HER2-) early breast cancer with high risk of recurrence.
Who can join: Review the eligibility criteria below.
Location: Southern Cancer Center, PC — Daphne, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (562 Sites)
Showing the first 25 of 562 sites.
- Southern Cancer Center, PC — Daphne, Alabama
- Ironwood Cancer and Research Centers — Chandler, Arizona
- Banner MD Anderson Cancer Center — Gilbert, Arizona
- Banner University Medical Center - Phoenix Campus (Banner Good Samaritan Medical Center) — Phoenix, Arizona
- Mayo Clinic — Scottsdale, Arizona
- Arizona Clinical Research Center, Inc. — Tucson, Arizona
- University of Arizona Cancer Center — Tucson, Arizona
- Highlands Oncology Group, PA — Springdale, Arkansas
- Comprehensive Blood & Cancer Center — Bakersfield, California
- UCSF Cancer Center Berkeley — Berkeley, California
- Cedars-Sinai Cancer Beverly Hills — Beverly Hills, California
- City of Hope National Medical Center — Duarte, California
- UCSF Wash Cancer CNTR — Fremont, California
- City of Hope at Irvine Lennar — Irvine, California
- UC San Diego Moores Cancer Center — La Jolla, California
- Helios Clinical Research — Long Beach, California
- Cancer and Blood Research Center, LLC — Los Alamitos, California
- USC/Norris Comprehensive Cancer Center — Los Angeles, California
- UCLA Department of Medicine - Hematology/Oncology — Los Angeles, California
- Pacific Cancer Care - Oncology — Monterey, California
- Hoag Memorial Hospital Presbyterian — Newport Beach, California
- UC Irvine Health, Chao Family Comprehensive Cancer Center — Orange, California
- Stanford Women's Cancer Center — Palo Alto, California
- Dignity Health dba Health Research Institute — Sacramento, California
- Sutter Institute for Medical Research — Sacramento, California
📞 Contact the Study Coordinator
Phone: (877) 332-7961
Email: clinicaltrials@menarinistemline.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.