Arterial Stiffness and Blood Pressure (NCT06495710)
Load-Dependent Arterial Stiffness to Optimize Blood Pressure Management in Older Veterans (LOADED BP)
🩺 Plain-English Summary (8th-Grade Level)
Hypertension is a common and treatable disorder that remains the leading preventable cause of heart disease. Blood pressure treatment relies mainly on upper arm blood pressure readings and ignores blood vessel physiology and underlying individual genetic information. Older Veterans with hypertension are less likely to be treated to goal blood pressure because there are conflicting recommendations for what constitutes "optimal" in older adults. The investigators have developed a novel way to non-invasively assess the components of blood vessel stiffness that is related to blood pressure (load-dependent stiffness). This project will generate new knowledge about how different blood pressure treatment goals (intensive vs standard) impact different components of arterial stiffness and if these differences can be explained through genetic analysis. Results from this project will offer the VA an updated blueprint for personalizing blood pressure care in older adults, ultimately improving cardiovascular health.
Who can join: Review the eligibility criteria below.
Location: Birmingham VA Medical Center, Birmingham, AL — Birmingham, Alabama
Age range: 60 Years
🧪 Interventions in This Study
- Blood pressure treatment algorithm (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- Birmingham VA Medical Center, Birmingham, AL — Birmingham, Alabama
- Tennessee Valley Healthcare System Nashville Campus, Nashville, TN — Nashville, Tennessee
- William S. Middleton Memorial Veterans Hospital, Madison, WI — Madison, Wisconsin
📞 Contact the Study Coordinator
Phone: (608) 256-1901
Email: adam.gepner@va.gov
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Hypertension
- Implementing a Home Blood Pressure Monitoring Program in Primary Care — New York, New York
- SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN — Birmingham, Alabama
- Stress and Blood Pressure Management for Caregivers — Columbus, Ohio
- Caveolin-1 and Vascular Dysfunction — Boston, Massachusetts
- The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension — Birmingham, Alabama
- Skills-Based Educational Strategies for Reduction of Vascular Events in Orange County — Irvine, California
Explore by condition: All Hypertension clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.