International CRDS Registry (NCT06508164)
International Calcium Release Deficiency Syndrome Registry
🩺 Plain-English Summary (8th-Grade Level)
Calcium Release Deficiency Syndrome (CRDS) is a newly discovered genetic arrhythmia syndrome that confers a risk of life-threatening arrhythmias secondary to RYR2 loss-of-function. The International CRDS registry has been designed to facilitate large-scale evaluation of CRDS, including its phenotypic spectrum, approaches to risk stratification, and optimal treatment strategies.
Who can join: Review the eligibility criteria below.
Location: University of California — San Francisco, California
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (20 Sites)
- University of California — San Francisco, California
- Mayo Clinic — Rochester, Minnesota
- Duke University — Durham, North Carolina
- Inova Health Care Services — Fairfax, Virginia
- Garvan Institute of Medical Research — Darlinghurst, New South Wales
- Antwerp University Hospital — Edegem, Antwerp
- Universitair Ziekenhuis Brussel — Brussels,
- University of Calgary — Calgary, Alberta
- Children's & Women's Health Centre of British Columbia — Vancouver, British Columbia
- The University of British Columbia — Vancouver, British Columbia
- Hamilton General Hospital — Hamilton, Ontario
- London Health Sciences Centre - University Hospital — London, Ontario
- Ottawa Heart Institute — Ottawa, Ontario
- Montréal Heart Institute — Montreal, Quebec
- Institut Universitaire de Cardiologie et de Pneumologie de Québec-Université Laval — Québec, Quebec
- Aarhus University Hospital — Aarhus,
- CHU de Bordeaux — Bordeaux, New Aquitaine
- Shaare Zedek Medical Center — Jerusalem,
- Oxford University Hospitals — Oxford, Oxfordshire
- City St George's, University of London — London,
📞 Contact the Study Coordinator
Phone: (905) 297-3479
Email: crds@phri.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Calcium Release Deficiency Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.