Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia (NCT06517641)
A Phase II Trial of Non-Myeloablative Conditioning and Transplantation of Haploidentical Related, Partially HLA-Mismatched, or Matched Unrelated Bone Marrow for Newly Diagnosed Patients With Severe Aplastic Anemia
๐ฉบ Plain-English Summary (8th-Grade Level)
BMT CTN 2207 will investigate the use of marrow transplantation for treatment of severe aplastic anemia that has not previously been treated.
Who can join: Review the eligibility criteria below.
Location: University of Alabama at Birmingham โ Birmingham, Alabama
Age range: 3 Years to 75 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (25 Sites)
- University of Alabama at Birmingham โ Birmingham, Alabama
- City of Hope โ Duarte, California
- University of California, Los Angeles โ Los Angeles, California
- Stanford University โ Stanford, California
- Moffitt Cancer Center โ Tampa, Florida
- Emory Winship Cancer Institute โ Atlanta, Georgia
- Blood and Marrow Transplant Center at Northside Hospital โ Atlanta, Georgia
- University of Kansas Medical Center โ Westwood, Kansas
- Johns Hopkins University โ Baltimore, Maryland
- Massachusetts General Hospital โ Boston, Massachusetts
- Dana Farber Cancer Institute โ Boston, Massachusetts
- Karmanos Cancer Institute โ Detroit, Michigan
- Mayo Clinic โ Rochester, Minnesota
- Washington University School of Medicine, Barnes-Jewish Hospital โ St Louis, Missouri
- Memorial Sloan Kettering Cancer Center โ New York, New York
- UNC Chapel Hill โ Chapel Hill, North Carolina
- Levine Cancer Institute โ Charlotte, North Carolina
- Duke University Health System โ Durham, North Carolina
- The Ohio State University โ Columbus, Ohio
- University of Oklahoma โ Oklahoma City, Oklahoma
- University of Pennsylvania โ Philadelphia, Pennsylvania
- Vanderbilt University โ Nashville, Tennessee
- Huntsman Cancer Institute โ Salt Lake City, Utah
- Fred Hutchinson Cancer Center โ Seattle, Washington
- Medical College of Wisconsin โ Milwaukee, Wisconsin
๐ Contact the Study Coordinator
Phone: (301) 251-1161
Email: bmtctn2207@emmes.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Severe Aplastic Anemia
- A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) โ Birmingham, Alabama
- Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppressive Therapy โ Bethesda, Maryland
- JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure โ Bethesda, Maryland
- Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia โ Bethesda, Maryland
- Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia โ Atlanta, Georgia
- Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome โ Bethesda, Maryland
Explore by condition: All Severe Aplastic Anemia clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.