Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy (NCT06529029)
Efficacy of Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy in Remission of Suicidal Ideation
🩺 Plain-English Summary (8th-Grade Level)
This protocol proposes an initial randomized clinical trial that includes all patients with suicidal ideation (SI) at baseline, and with SI as the primary outcome measure to examine whether Right Unilateral Low-Amplitude Pulse - Seizure Therapy (RUL LAP-ST) treatment has more magnitude and rate of remission of SI as conventional pulse amplitude Right Unilateral Electroconvulsive Therapy (RUL ECT) (based on our prior secondary analysis). Our central hypothesis is that RUL LAP-ST has significantly less cognitive/memory side effects (no memory side effects were noted in our prior studies for 500mA and 600mA) and thus is more favorable in terms of side effects compared to RUL conventional pulse amplitude ECT, while maintaining better anti-suicidal effect.
Who can join: Review the eligibility criteria below.
Location: Pine Rest Christian Mental Health Services — Grand Rapids, Michigan
Age range: 18 Years to 90 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Pine Rest Christian Mental Health Services — Grand Rapids, Michigan
📞 Contact the Study Coordinator
Phone: (616) 281-6451
Email: nagy.youssef@pinerest.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Suicidal Ideation
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- A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior — Boston, Massachusetts
- Youth Suicide Prevention: CAMS-BI vs. Safety Planning in a Randomized Trial — Cleveland, Ohio
- Neural Correlates of Suicidal Behavior in Youth — Cleveland, Ohio
- Task-Shifting Adapted IPT-A for Youth Suicide Prevention — Chestnut Hill, Massachusetts
Explore by condition: All Suicidal Ideation clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.