Who is eligible for clinical trial NCT06533059?

Participants must meet protocol criteria for Cancer. Confirm exact inclusion and exclusion requirements with the study coordinator.

Does clinical trial NCT06533059 provide travel or cost reimbursement?

Check with the site coordinator at the participating facility for travel and lodging stipend availability, and for which routine-care costs are covered.

🏛️ Verified NIH Record • Updated 2026-07-14

A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors (NCT06533059)

AKTive-001: A Phase 1/1b Multiple Cohort Trial of ALTA2618 in Patients With Advanced Solid Tumors With AKT1 E17K Mutation

🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic Sponsor: Alterome Therapeutics, Inc.

🩺 Plain-English Summary (8th-Grade Level)

The purpose of this study is to characterize the safety and tolerability of ALTA2618 in adults with AKT1 E17K-mutant advanced solid tumors.

Who can join: Review the eligibility criteria below.

Location: Research Site — La Jolla, California

Age range: 18 Years

🧪 Interventions in This Study

ALTA2618 (DRUG)

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (31 Sites)

Showing the first 25 of 31 sites.

Research Site — La Jolla, California
Research Site — Denver, Colorado
Research Site — Sarasota, Florida
Research Site — Boston, Massachusetts
Research Site — Boston, Massachusetts
Research Site — St Louis, Missouri
Research Site — Nashville, Tennessee
Research Site — Houston, Texas
Research Site #2 — San Antonio, Texas
Research Site — San Antonio, Texas
Research Site — Fairfax, Virginia
Research Site — Madison, Wisconsin
Research Site — Randwick, New South Wales
Research Site — Malvern, Victoria
Research Site — Nedlands, Western Australia
Research Site — Caen,
Research Site — Villejuif,
Research Site — Kyoto,
Research Site — Tokyo,
Research Site — Seoul,
Research Site — Seoul,
Research Site — Barcelona,
Research Site — Barcelona,
Research Site — Madrid,
Research Site — Madrid,

💰 Cost, Insurance & Patient Rights

100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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💡 How to Participate

Check the checklist above to see if you may qualify.
Review the official NIH record below to find the coordinating site.
Ask about the visit schedule, what is covered at no cost, and any travel support.
Confirm with your own doctor before making a decision.

🏛️ View Official NIH Record ↗