๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-09-30

MB-105 in Patients With CD5 Positive T-cell Lymphoma (NCT06534060)

A Phase 2, Open-label, Multicenter Study of MB-105 in Patients With CD5 Positive (CD5+) Relapsed / Refractory T-cell Lymphoma (r/r TCL).

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: March Biosciences Inc

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a single arm, two-stage, Phase 2, open-label, multicenter study of MB-105 in patients with CD5 Positive (CD5+) Relapsed / Refractory T-cell Lymphoma (r/r TCL). This study will apply a Simon two-stage optimal design.

Who can join: Review the eligibility criteria below.

Location: University of San Diego (UCSD)-Moores Cancer Center โ€” San Diego, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (12 Sites)

  • University of San Diego (UCSD)-Moores Cancer Center โ€” San Diego, California
  • SCRI - Colorado Blood Cancer Institute (CBCI) โ€” Denver, Colorado
  • Moffitt Cancer Center Magnolia Campus โ€” Tampa, Florida
  • University of Iowa โ€” Iowa City, Iowa
  • Massachusetts General Hospital โ€” Boston, Massachusetts
  • University of Nebraska โ€” Omaha, Nebraska
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • University of North Carolina at Chapel Hill โ€” Chapel Hill, North Carolina
  • Cleveland Clinic โ€” Cleveland, Ohio
  • Oregan Health & Science University โ€” Portland, Oregon
  • Baylor College of Medicine โ€” Houston, Texas
  • MD Anderson Cancer Center โ€” Houston, Texas

๐Ÿ“ž Contact the Study Coordinator

Phone: (713) 898-0838

Email: clinicaltrials@march.bio

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—