Zopa Retreatment and Vector Shedding in Adults With RRP (NCT06538480)
Open-Label Study of Zopapogene Imadenovec Retreatment and Vector Shedding Evaluation in Adult Patients With Recurrent Respiratory Papillomatosis
🩺 Plain-English Summary (8th-Grade Level)
This open-label study evaluates safety, vector shedding, and retreatment efficacy of Zopapogene imadenovec (Zopa) in adults with recurrent respiratory papillomatosis (RRP). Two cohorts will be enrolled (n=30): Cohort 1 to assess the magnitude and duration of adenoviral vector shedding in urine, feces, skin, and nasal tissue; Cohort 2 to assess the complete response rate following retreatment.
Who can join: Review the eligibility criteria below.
Location: Winship Cancer Institute, Emory University — Atlanta, Georgia
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- Winship Cancer Institute, Emory University — Atlanta, Georgia
- National Institute of Health — Bethesda, Maryland
- University of Cincinnati — Cincinnati, Ohio
📞 Contact the Study Coordinator
Phone: (301) 556-9900
Email: clinicaltrials@precigen.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Recurrent Respiratory Papillomatosis
- Adjuvant PRGN-2012 in Adult Patients With Recurrent Respiratory Papillomatosis — Bethesda, Maryland
- Autologous Dendritic Cell Vaccine For Recurrent Respiratory Papillomatosis (RRP) Patients — Scottsdale, Arizona
- The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP) — New Haven, Connecticut
Explore by condition: All Recurrent Respiratory Papillomatosis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.