🏛️ Verified NIH Record • Updated 2026-01-13
Study to Evaluate the Effect on Obesity of QW Nimacimab and QW Nimacimab Co-administered With Semaglutide vs Placebo (NCT06577090)
A Phase 2 Study of QW Nimacimab Injection, Compared to Placebo Injection and QW Weekly Nimacimab Injection Co-administered With Semaglutide in Participants Who Are Overweight or Obese
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Skye Bioscience, Inc.
🩺 Plain-English Summary (8th-Grade Level)
This is a proof-of-concept study to assess the safety and efficacy of Nimacimab Injection compared to an active and placebo injection control.
Who can join: Review the eligibility criteria below.
Location: Pinnacle Research Group — Anniston, Alabama
Age range: 18 Years to 65 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (16 Sites)
- Pinnacle Research Group — Anniston, Alabama
- Diablo Clinical Research, Inc. — Walnut Creek, California
- Chase Medical Research, LLC — Waterbury, Connecticut
- ACCEL Research Sites — Atlanta, Georgia
- Center for Advanced Research & Education — Gainesville, Georgia
- L-MARC Research Center — Louisville, Kentucky
- Be Well Clinical Studies — Lincoln, Nebraska
- Palm Research Center — Las Vegas, Nevada
- ActivMed Practices & Research — Portsmouth, New Hampshire
- Weill Cornell Medicine — New York, New York
- Accellacare of Wilmington — Wilmington, North Carolina
- Lillestol Research, LLC — Fargo, North Dakota
- Velocity Clinical Research, Dallas — Dallas, Texas
- Be Well Clinical Studies — Round Rock, Texas
- Charlottesville Medical Research — Charlottesville, Virginia
- Rainier Clinical Research Center — Renton, Washington
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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Explore by condition: All Obesity clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.