ASSESS ALL ALS Study (NCT06578195)
ASSESS ALL ALS - Longitudinal Biomarker Study for Symptomatic ALS and Control Participants
🩺 Plain-English Summary (8th-Grade Level)
The ALL ALS Clinical Research Consortium is establishing research to collect a wide range of samples, clinical information and measurements from Amyotrophic Lateral Sclerosis (ALS) symptomatic, ALS gene carriers and control cohorts. This consortium is being funded by the National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS) and managed by two clinical coordinating centers (CCC) at Barrow Neurological Institute and Massachusetts General Hospital. The clinical sites are distributed across the country, and led by a group of collaborative principal investigators. Once data and samples are collected and harmonized, it will be made available to research community for future research into ALS and related neurological diseases. ASSESS protocol is specific for symptomatic ALS and control participants. This protocol includes both on-site and off-site(remote) participants. The participants will be followed for 24 months (2 years), and will include collection of medical history, clinical outcomes, and blood samples once in 4 months. Additionally, the participants will complete patient reported outcomes and speech recordings once a month. Participants who are coming into clinic may also provide optional Cerebrospinal Fluid (CSF) samples.
Who can join: Review the eligibility criteria below.
Location: University of Alabama Birmingham — Birmingham, Alabama
Age range: 18 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (37 Sites)
Showing the first 25 of 37 sites.
- University of Alabama Birmingham — Birmingham, Alabama
- Barrow Neurological Institute — Phoenix, Arizona
- University of California, Irvine — Irvine, California
- University of California San Diego — La Jolla, California
- University of California, Los Angeles — Los Angeles, California
- University of California, San Francisco — San Francisco, California
- University of Colorado Anschutz Medical Campus — Aurora, Colorado
- Hospital For Special Care — New Britain, Connecticut
- Georgetown University — Washington D.C., District of Columbia
- Nova Southeastern University — Davie, Florida
- Mayo Clinic — Jacksonville, Florida
- Saint Alphonsus Regional Medical Center — Boise, Idaho
- Northwestern University — Chicago, Illinois
- Synapticure (Remote Participation Only) — Chicago, Illinois
- Indiana University — Indianapolis, Indiana
- John Hopkins University — Baltimore, Maryland
- Nih/Ninds — Bethseda, Maryland
- Massachusetts General Brigham — Boston, Massachusetts
- University of Michigan — Ann Arbor, Michigan
- Henry Ford Health — Detroit, Michigan
- University of Minnesota — Minneapolis, Minnesota
- Washington University — St Louis, Missouri
- University of Nebraska Medical Center — Omaha, Nebraska
- Dartmouth Hitchcock Medical Center — Lebanon, New Hampshire
- Columbia University — New York, New York
📞 Contact the Study Coordinator
Phone: (602) 845-0248
Email: info@all-als.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.