๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-21

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors (NCT06586515)

A Phase 1a/1b Trial of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Eli Lilly and Company

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The main purpose of this study is to assess safety \& tolerability and antitumor activity of LY3962673 as monotherapy and in combination with other chemotherapy agents in participants with KRAS G12D-mutant advanced solid tumor types. The study is expected to last approximately 5 years.

Who can join: Review the eligibility criteria below.

Location: City of Hope โ€” Duarte, California

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (52 Sites)

Showing the first 25 of 52 sites.

  • City of Hope โ€” Duarte, California
  • University of California, Los Angeles (UCLA) โ€” Santa Monica, California
  • Sarah Cannon Research Institute at HealthOne โ€” Denver, Colorado
  • Sibley Memorial Hospital โ€” Washington D.C., District of Columbia
  • Florida Cancer Specialists - Lake Nona - Sarah Cannon Research Institute โ€” Orlando, Florida
  • Emory University School of Medicine โ€” Atlanta, Georgia
  • Community Health Network โ€” Indianapolis, Indiana
  • Massachusetts General Hospital โ€” Boston, Massachusetts
  • Dana-Farber Cancer Institute โ€” Boston, Massachusetts
  • Barbara Ann Karmanos Cancer Institute โ€” Detroit, Michigan
  • South Texas Accelerated Research Therapeutics (START) Midwest โ€” Grand Rapids, Michigan
  • New York University (NYU) Langone Medical Center โ€” New York, New York
  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • Duke University Medical Center โ€” Durham, North Carolina
  • University of Cincinnati (UC) - Cancer Institute โ€” Cincinnati, Ohio
  • Cleveland Clinic โ€” Cleveland, Ohio
  • University of Pittsburgh Medical Center (UPMC) - Hillman Cancer Center โ€” Pittsburgh, Pennsylvania
  • Sarah Cannon Research Institute โ€” Nashville, Tennessee
  • USO - US Oncology Research Network โ€” Nashville, Tennessee
  • Vanderbilt University School of Medicine โ€” Nashville, Tennessee
  • MD Anderson Cancer Center โ€” Houston, Texas
  • South Texas Accelerated Research Therapeutics (START) โ€” San Antonio, Texas
  • Huntsman Cancer Institute โ€” Salt Lake City, Utah
  • Fred Hutchinson Cancer Center โ€” Seattle, Washington
  • University of Wisconsin - Carbone Cancer Center โ€” Madison, Wisconsin

๐Ÿ“ž Contact the Study Coordinator

Phone: (317) 615-4559

Email: LillyTrials@Lilly.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—