A Trial to Evaluate Efficacy and Safety of Buloxibutid in People With Idiopathic Pulmonary Fibrosis. (NCT06588686)
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Trial Evaluating the Efficacy and Safety of 2 Doses of Buloxibutid Over 52 Weeks in People With Idiopathic Pulmonary Fibrosis.
🩺 Plain-English Summary (8th-Grade Level)
The ASPIRE trial is a 52 week randomized, double-blind, placebo-controlled, parallel-group, multicenter trial in which the efficacy, safety, and pharmacokinetics of orally administered buloxibutid, either on top of stable IPF therapy or as monotherapy, are assessed in participants with IPF. Trial website: www.aspire-ipf.com
Who can join: Review the eligibility criteria below.
Location: UAB Hospital, School of Medicine/Lung Health Center — Birmingham, Alabama
Age range: 40 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (104 Sites)
Showing the first 25 of 104 sites.
- UAB Hospital, School of Medicine/Lung Health Center — Birmingham, Alabama
- Paradigm Clinical Research Centers, Inc. — Redding, California
- UC Davis Health System — Sacramento, California
- UC San Diego Medical Center - Hillcrest — San Diego, California
- Paradigm Clinical Research — San Diego, California
- National Jewish Medical and Research Center — Denver, Colorado
- University of Florida Health (UF Health) — Gainesville, Florida
- Clinical Research Specialists — Kissimmee, Florida
- Emory Saint Joseph's Hospital — Atlanta, Georgia
- Endeavor Health - Evanston Hospital — Evanston, Illinois
- University of Kansas Medical Center — Kansas City, Kansas
- William Beaumont Hospital - Royal Oak — Royal Oak, Michigan
- Renown Clinical Research — Reno, Nevada
- Southeastern Research Center — Winston-Salem, North Carolina
- Cleveland Clinic - Cleveland, Department of Pulmonary Medicine — Cleveland, Ohio
- Summit Health - Bend — Bend, Oregon
- Oregon Clinic, Pulmonary, Critical Care & Sleep Medicine East — Portland, Oregon
- Temple University Hospital — Philadelphia, Pennsylvania
- Low Country Lung and Critical Care — North Charleston, South Carolina
- Baylor Scott & White Research Institute — Dallas, Texas
- El Paso Pulmonary Association — El Paso, Texas
- University of Utah, Health Sciences Center — Salt Lake City, Utah
- University of Wisconsin Clinical Science Center — Madison, Wisconsin
- Research Institute of Respiratory Diseases — San Miguel de Tucumán, Tucumán Province
- CEMER Medical Center for Respiratory Diseases — Buenos Aires,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Idiopathic Pulmonary Fibrosis (IPF)
- Saracatinib in the Treatment of Idiopathic Pulmonary Fibrosis — Denver, Colorado
- A Comparison of a Medication Adherence Platform (FORTISKAP™) vs. Usual Care in Subjects on Oral Medications for the Treatment of Interstitial Lung Disease, Sarcoid and Pulmonary Hypertension — Norfolk, Virginia
- Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone in Adults With Idiopathic Pulmonary Fibrosis (IPF) — Palm Spring, California
- The Genetics of Pulmonary Fibrosis — Aurora, Colorado
- Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis — Birmingham, Alabama
Explore by condition: All Idiopathic Pulmonary Fibrosis (IPF) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.