A Study to Investigate the Safety and Efficacy of mRNA-1403 in Participants ≥18 Years of Age for the Prevention of Acute Gastroenteritis (NCT06592794)
A Phase 3, Randomized, Observer-blinded, Placebo-controlled Study to Evaluate the Safety and Efficacy of mRNA-1403, a Multivalent Candidate Vaccine to Prevent Norovirus Acute Gastroenteritis in Adults ≥18 Years of Age
🩺 Plain-English Summary (8th-Grade Level)
The primary objectives of this study are to evaluate the safety and reactogenicity of mRNA-1403, and to demonstrate the efficacy of mRNA-1403 to prevent protocol-defined moderate or severe norovirus acute gastroenteritis (AGE) associated with vaccine matched genotypes.
Who can join: Review the eligibility criteria below.
Location: Accel Research Sites - Achieve Clinical Research — Birmingham, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (283 Sites)
Showing the first 25 of 283 sites.
- Accel Research Sites - Achieve Clinical Research — Birmingham, Alabama
- Cullman Clinical Trials — Cullman, Alabama
- Alliance for Multispecialty Research, LLC — Daphne, Alabama
- ClinMed, LLC — Phoenix, Arizona
- DM Clinical - Phoenix — Phoenix, Arizona
- HOPE Research Institute — Phoenix, Arizona
- HOPE Research Institute — Phoenix, Arizona
- Abby's Research Institute — Phoenix, Arizona
- Headlands Research Scottsdale — Scottsdale, Arizona
- Scottsdale Clinical Trials — Scottsdale, Arizona
- Hope Research Institute - Tempe — Tempe, Arizona
- Arizona Liver Health — Tucson, Arizona
- Quality of Life Medical and Research Center — Tucson, Arizona
- Del Sol Research Management LLC.- Tucson — Tucson, Arizona
- Lynn Institute of the Ozarks — Little Rock, Arkansas
- Baptist Health Center for Clinical Research — Little Rock, Arkansas
- ARK Clinical Research, LLC — Fountain Valley, California
- ASCADA Research, LLC - Family Medicine — Fullerton, California
- Matrix Clinical Research — Huntington Park, California
- Velocity Clinical Research, San Diego — La Mesa, California
- Ark Clinical Research — Long Beach, California
- Matrix Clinical Research — Los Angeles, California
- Velocity Clinical Research - Westlake — Los Angeles, California
- Paradigm Research — Redding, California
- Artemis Institute for Clinical Research — Riverside, California
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Acute Gastroenteritis
- Fortified Oral Rehydration Therapy for Pediatric Diarrhea — New Brunswick, New Jersey
Explore by condition: All Acute Gastroenteritis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.