A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes (NCT06603571)
A Phase 2, Parallel-Group, Double-Blind, Placebo-Controlled Study to Investigate Weight Management With LY3841136 and Tirzepatide, Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes
🩺 Plain-English Summary (8th-Grade Level)
The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to investigate the safety and efficacy of LY3841136 for chronic weight management alone or in combination with Tirzepatide across a wide dose range in participants with Type 2 Diabetes. Participation in the study will last about 64 weeks.
Who can join: Review the eligibility criteria below.
Location: The Institute for Liver Health II dba Arizona Clinical Trials - Mesa — Chandler, Arizona
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (52 Sites)
Showing the first 25 of 52 sites.
- The Institute for Liver Health II dba Arizona Clinical Trials - Mesa — Chandler, Arizona
- HOPE Research Institute — Phoenix, Arizona
- Headlands Research - Scottsdale — Scottsdale, Arizona
- The Institute for Liver Health II dba Arizona Liver Health-Tucson — Tucson, Arizona
- NorCal Medical Research, Inc — Greenbrae, California
- Velocity Clinical Research, Huntington Park — Huntington Park, California
- Peninsula Research Associates — Rolling Hills Estates, California
- Diablo Clinical Research, Inc. — Walnut Creek, California
- Stamford Therapeutics Consortium — Stamford, Connecticut
- Northeast Research Institute (NERI) — Fleming Island, Florida
- Indago Research & Health Center, Inc — Hialeah, Florida
- New Horizon Research Center — Miami, Florida
- Suncoast Clinical Research, Inc. — New Port Richey, Florida
- Charter Research - Winter Park — Orlando, Florida
- Charter Research - Lady Lake — The Villages, Florida
- Medical Research Partners — Ammon, Idaho
- Great Lakes Clinical Trials - Andersonville — Chicago, Illinois
- Great Lakes Clinical Trials - Ravenswood — Chicago, Illinois
- NorthShore University Health System — Skokie, Illinois
- Iowa Diabetes and Endocrinology Research Center — West Des Moines, Iowa
- Cotton O'Neil Diabetes & Endocrinology — Topeka, Kansas
- Knownwell — Needham, Massachusetts
- Lucida Clinical Trials — New Bedford, Massachusetts
- Headlands Research - Detroit — Southfield, Michigan
- Arcturus Healthcare , PLC, Troy Internal Medicine Research Division — Troy, Michigan
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.