The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma (NCT06606119)
🩺 Plain-English Summary (8th-Grade Level)
Traumatic injury followed by critical illness provokes pathophysiologic changes in the bone marrow and the gut that contribute to persistent anemia and changes in the microbiome which significantly impact long-term recovery. This project will define the interactions between the stress, chronic inflammation, bone marrow dysfunction, and an altered microbiome which will provide a strong foundation for future clinical interventions to help improve outcomes following severe trauma.
Who can join: Review the eligibility criteria below.
Location: UF Academic Research Building — Gainesville, Florida
Age range: 18 Years to 100 Years
🧪 Interventions in This Study
- Data and tissue collection (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- UF Academic Research Building — Gainesville, Florida
- UF Health at Shands Hospital — Gainesville, Florida
- UF Laboratory of Inflammation Biology and Surgical Science and Shands Hospital at UF — Gainesville, Florida
📞 Contact the Study Coordinator
Phone: (352) 273-8759
Email: ruth.davis@surgery.ufl.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Hematopoietic Stem Cell Dysfunction in the Elderly After Severe Injury — Gainesville, Florida
Explore by condition: All Trauma Injury clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.