A Phase Ib Study of Rezatapopt in Combination With Azacitidine in Patients With TP53Y220C Mutant Myeloid Malignancies (Acute Myeloid Leukemia or Myelodysplastic Syndrome) (NCT06616636)

🧪 Interventions in This Study

• Azacitidine (DRUG)
• Rezatapopt (DRUG)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (2 Sites)

• Moffitt Cancer Center — Tampa, Florida
• The University of Texas MD Anderson Cancer Center — Houston, Texas

📞 Contact the Study Coordinator

Phone: (713) 794-1141

Email: cdinardo@mdanderson.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Myelodysplastic Syndrome

• Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders — Basking Ridge, New Jersey
• A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies — Birmingham, Alabama
• Revisiting the Universal Donor: Does Exposure to O Blood Products Affect Patient Outcomes? — Hamilton, Ontario
• Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial) — Berkeley, California
• A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions — Gilbert, Arizona

Explore by condition: All Myelodysplastic Syndrome clinical trials

💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Contact the study coordinator using the phone/email above.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.