๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-05

A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (NCT06624085)

A Phase Ib Study Evaluating the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of Glofitamab in Combination With Gemcitabine Plus Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

๐Ÿ”ต Active, Not Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Hoffmann-La Roche

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of the study is to evaluate glofitamab + gemcitabine + oxaliplatin in participants in the United States, including under-represented racial and ethnic populations, that have relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL).

Who can join: Review the eligibility criteria below.

Location: UC San Diego Moores Cancer Center โ€” La Jolla, California

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (17 Sites)

  • UC San Diego Moores Cancer Center โ€” La Jolla, California
  • Saddleback Memorial Medical Center โ€” Laguna Hills, California
  • Hoag Memorial Hospital โ€” Newport Beach, California
  • University of California Los Angeles (UCLA) - Cancer Care - Santa Monica โ€” Santa Monica, California
  • Georgetown University โ€” Washington D.C., District of Columbia
  • AdventHealth Cancer Institute โ€” Orlando, Florida
  • Winship Cancer Institute of Emory University โ€” Atlanta, Georgia
  • University of Illinois Cancer Center โ€” Chicago, Illinois
  • Kansas City VA Medical Center โ€” Kansas City, Kansas
  • Christus Health - Christus St. Vincent Regional Medical Center โ€” Santa Fe, New Mexico
  • Stony Brook Univ Cancer Ctr โ€” Stony Brook, New York
  • East Carolina University โ€” Greenville, North Carolina
  • Thomas Jefferson University โ€” Philadelphia, Pennsylvania
  • Renovatio Clinical - El Paso โ€” El Paso, Texas
  • Baylor College of Medicine โ€” Houston, Texas
  • Renovatio Clinical โ€” The Woodlands, Texas
  • Auxilio Mutuo Cancer Center โ€” San Juan,

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Lymphoma clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—