๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-17

Safety of Anal Curcumin (NCT06626230)

An Incremental Dose Escalation Trial of Safety and Tolerability of Curcumin

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Lisa Flowers

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to see if curcumin can reverse anal high-grade squamous intraepithelial lesions (aHSIL) (high-grade anal precancerous cells or high-grade abnormal cells) in people living with HIV to avoid current treatments such as ablation (destroying abnormal cells with heat or surgical excision (cutting out the abnormal cells)), which have potential short- and long-term side effects.

Who can join: Review the eligibility criteria below.

Location: Grady Memorial Hospital โ€” Atlanta, Georgia

Age range: 30 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (2 Sites)

  • Grady Memorial Hospital โ€” Atlanta, Georgia
  • Grady Hospital - Ponce De Leon Clinic โ€” Atlanta, Georgia

๐Ÿ“ž Contact the Study Coordinator

Phone: (404) 251-8931

Email: lflowe2@emory.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Anal High Grade Squamous Intraepithelial Lesion

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—