๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-13

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC (NCT06627647)

A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line Treatment of Patients With Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer Whose Tumors Express PD-L1 (ARTEMIDE-Lung03)

๐ŸŸข Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: AstraZeneca

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of ARTEMIDE-Lung03 is to evaluate the efficacy and safety of rilvegostomig compared to pembrolizumab, both in combination with platinum-based doublet chemotherapy, as a first-line treatment of patients with locally advanced or metastatic non-squamous NSCLC whose tumors express PD-L1.

Who can join: Review the eligibility criteria below.

Location: Research Site โ€” Mobile, Alabama

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (295 Sites)

Showing the first 25 of 295 sites.

  • Research Site โ€” Mobile, Alabama
  • Research Site โ€” Chandler, Arizona
  • Research Site โ€” Phoenix, Arizona
  • Research Site โ€” Anaheim, California
  • Research Site โ€” Beverly Hills, California
  • Research Site โ€” Loma Linda, California
  • Research Site โ€” Redlands, California
  • Research Site โ€” San Diego, California
  • Research Site โ€” San Francisco, California
  • Research Site โ€” Santa Rosa, California
  • Research Site โ€” Walnut Creek, California
  • Research Site โ€” Lone Tree, Colorado
  • Research Site โ€” Stamford, Connecticut
  • Research Site โ€” West Haven, Connecticut
  • Research Site โ€” Newark, Delaware
  • Research Site โ€” Bay Pines, Florida
  • Research Site โ€” Fort Lauderdale, Florida
  • Research Site โ€” Gainesville, Florida
  • Research Site โ€” Jacksonville, Florida
  • Research Site โ€” Miami, Florida
  • Research Site โ€” Ocala, Florida
  • Research Site โ€” St. Petersburg, Florida
  • Research Site โ€” Atlanta, Georgia
  • Research Site โ€” Boise, Idaho
  • Research Site โ€” Chicago, Illinois

๐Ÿ“ž Contact the Study Coordinator

Phone: (877) 240-9479

Email: information.center@astrazeneca.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—