πŸ›οΈ Verified NIH Record β€’ Updated 2026-08-20

A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer. (NCT06629779)

A PHASE 3, RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED STUDY OF PF-06821497 (MEVROMETOSTAT) WITH ENZALUTAMIDE IN METASTATIC CASTRATION RESISTANT PROSTATE CANCER (MEVPRO-2)

🟒 Recruiting Phase3 πŸ’Š Investigational Drug / Biologic Sponsor: Pfizer

🩺 Plain-English Summary (8th-Grade Level)

This study will explore whether a combination of the investigational drug PF-06821497 and enzalutamide will work better than taking enzalutamide alone in participants with mCRPC who are ARSi or abiraterone naΓ―ve.

Who can join: Review the eligibility criteria below.

Location: Ironwood Cancer & Research Centers β€” Chandler, Arizona

Age range: 18 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (236 Sites)

Showing the first 25 of 236 sites.

  • Ironwood Cancer & Research Centers β€” Chandler, Arizona
  • Ironwood Cancer & Research Centers β€” Gilbert, Arizona
  • Palo Verde Hematology Oncology β€” Glendale, Arizona
  • Ironwood Cancer & Research Centers β€” Glendale, Arizona
  • Ironwood Cancer & Research Centers β€” Goodyear, Arizona
  • Ironwood Cancer & Research Centers β€” Mesa, Arizona
  • Ironwood Cancer & Research Centers β€” Mesa, Arizona
  • Ironwood Cancer & Research Centers β€” Phoenix, Arizona
  • Ironwood Cancer & Research Centers β€” Scottsdale, Arizona
  • Highlands Oncology β€” Fayetteville, Arkansas
  • Arkansas Urology - Little Rock β€” Little Rock, Arkansas
  • Highlands Oncology β€” Rogers, Arkansas
  • Highlands Oncology Group β€” Springdale, Arkansas
  • Los Angeles Cancer Network (LACN) β€” Anaheim, California
  • Los Angeles Cancer Network (LACN) β€” Fountain Valley, California
  • Los Angeles Cancer Network (LACN) β€” Glendale, California
  • Los Angeles Cancer Network (LACN) β€” Glendale, California
  • Los Angeles Cancer Network (LACN) β€” Laguna Hills, California
  • Los Angeles Cancer Network (LACN) β€” Los Angeles, California
  • Los Angeles Cancer Network (LACN) β€” Los Angeles, California
  • Medical Oncology Associates of San Diego β€” San Diego, California
  • Accellacare of Duly β€” Lisle, Illinois
  • Duly Health and Care (Bone Scintigraphy) β€” Lisle, Illinois
  • Blessing Hospital β€” Quincy, Illinois
  • Blessing Physician Services β€” Quincy, Illinois

πŸ“ž Contact the Study Coordinator

Phone: (800) 718-1021

Email: ClinicalTrials.gov_Inquiries@pfizer.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—