๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-17

ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies (NCT06656494)

A Phase 1 Study of ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies.

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Beijing InnoCare Pharma Tech Co., Ltd.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

Evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of ICP-248 in combination with azacitidine in patients with acute myelogenous leukemia and Myelodysplastic Syndromes.

Who can join: Review the eligibility criteria below.

Location: Chao Family Comprehensive Cancer Center, University of California, Irvine โ€” Orange, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (22 Sites)

  • Chao Family Comprehensive Cancer Center, University of California, Irvine โ€” Orange, California
  • Yale University, Yale Cancer Center โ€” New Haven, Connecticut
  • H Lee Moffitt Cancer Center & Research Institute โ€” Tampa, Florida
  • NYU Langone Health โ€” New York, New York
  • University of North Carolina at Chapel Hill โ€” Chapel Hill, North Carolina
  • Medical College of Wisconsin โ€” Milwaukee, Wisconsin
  • St Vincent's Hospital โ€” Sydney, New South Wales
  • Royal Perth Hospital โ€” Perth, Western Australia
  • Anhui Provincial Hospita โ€” Hefei, Anhui
  • Peking University People's Hospital โ€” Beijing, Beijing Municipality
  • The First Affiliated Hospital of Chongqing Medical University โ€” Chongqing, Chongqing Municipality
  • Guangdong Provincial People's Hospital โ€” Guangzhou, Guangdong
  • Nanfang Hospital Southern Medical University โ€” Guangzhou, Guangdong
  • Henan Cancer Hospital โ€” Zhengzhou, Henan
  • Union Hospital Tongji Medical College Huazhong University of Science and Technology โ€” Wuhan, Hubei
  • The First Affiliated Hospital of Soochow University โ€” Suzhou, Jiangsu
  • The First Affiliated Hospital of Nanchang University โ€” Nanchang, Jiangxi
  • The First Hospital of Jilin University โ€” Changchun, Jilin
  • Shengjing Hospital of China Medical University โ€” Shengyang, Liaoning
  • Sichuan Provincial People's Hospital โ€” Chengdu, Sichuan
  • Tianjin People's Hospital โ€” Tianjin, Tianjin Municipality
  • The First Affiliated Hospital, Zhejiang University School of Medicine โ€” Hangzhou, Zhejiang

๐Ÿ“ž Contact the Study Coordinator

Phone: 010-66609745

Email: CO_HGRAC@innocarepharma.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—