๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-23

Response to Exercise and Nitric Oxide in PAD (NCT06657976)

Response to Exercise and Nitric Oxide in Peripheral Artery Disease: The RESIST PAD Trial

๐ŸŸข Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Northwestern University

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

RESIST PAD is a randomized trial of 200 PAD patients to establish: 1) whether a 12-week exercise intervention significantly increases ฮ” nitrite at 12-week follow-up, compared to control; 2) whether exercise "responders" have greater ฮ” nitrite increases compared to "non-responders"; 3) among non-responders, whether supplementing exercise with nitrate-rich beetroot juice between weeks 13-24 increases ฮ” nitrite and improves 6-minute walk at 24-week follow-up.

Who can join: Review the eligibility criteria below.

Location: Northwestern University Feinberg School of Medicine โ€” Chicago, Illinois

Age range: 50 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (2 Sites)

  • Northwestern University Feinberg School of Medicine โ€” Chicago, Illinois
  • University of Chicago โ€” Chicago, Illinois

๐Ÿ“ž Contact the Study Coordinator

Phone: (312) 503-6419

Email: mdm608@northwestern.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—