๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-11-20

A Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM) (NCT06660173)

A Study to Evaluate the Efficacy, Safety & Tolerability of Maridebart Cafraglutide in Adults With T2DM

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Amgen

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The main purpose of this study is to assess the dose-response relationship of maridebart cafraglutide on glucose control compared with placebo.

Who can join: Review the eligibility criteria below.

Location: Accel Research Site - Birmingham Clinical Research Unit โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (96 Sites)

Showing the first 25 of 96 sites.

  • Accel Research Site - Birmingham Clinical Research Unit โ€” Birmingham, Alabama
  • Anaheim Clinical Trials โ€” Anaheim, California
  • Hope Clinical Research LLC โ€” Canoga Park, California
  • Orange County Research Center โ€” Lake Forest, California
  • San Jose Clinical Trials โ€” San Jose, California
  • Northeast Research Institute - Neri โ€” Fleming Island, Florida
  • New Horizon Research Center โ€” Miami, Florida
  • Florida Institute for Clinical Research โ€” Orlando, Florida
  • Conquest Research - Winter Park โ€” Winter Park, Florida
  • Accel Research Site - Neurostudies โ€” Decatur, Georgia
  • Cedar Crosse Research and Health Care โ€” Chicago, Illinois
  • Tandem Clinical Research - Marrero โ€” Marrero, Louisiana
  • DM Clinical - Detroit โ€” Southfield, Michigan
  • Montana Medical Research โ€” Missoula, Montana
  • Physicians East โ€” Greenville, North Carolina
  • Diabetes and Endocrinology Associates of Stark County Inc โ€” Canton, Ohio
  • Alliance for Multispecialty Research โ€” Norman, Oklahoma
  • Trial Management Associates - Myrtle Beach โ€” Myrtle Beach, South Carolina
  • FutureSearch Trials of Neurology โ€” Austin, Texas
  • Velocity Clinical Research - Dallas โ€” Dallas, Texas
  • DM Clinical Research - Cyfair Clinical Research Center โ€” Houston, Texas
  • Southern Endocrinology Associates PA โ€” Mesquite, Texas
  • Be Well Clinical Studies โ€” Round Rock, Texas
  • Diabetes and Glandular Disease Clinic โ€” San Antonio, Texas
  • DM Clinical Research - Martin Diagnostic Clinic โ€” Tomball, Texas

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—