🏛️ Verified NIH Record • Updated 2026-07-17
A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity (NCT06662383)
A Phase 3, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Retatrutide Compared to Tirzepatide in Adults Who Have Obesity
🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: Eli Lilly and Company
🩺 Plain-English Summary (8th-Grade Level)
The main purpose of this study is to evaluate the efficacy and safety of retatrutide compared to tirzepatide in adults who have obesity. The study will last about 89 weeks.
Who can join: Review the eligibility criteria below.
Location: Medical Advancement Centers of Arizona — Tempe, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (65 Sites)
Showing the first 25 of 65 sites.
- Medical Advancement Centers of Arizona — Tempe, Arizona
- Mary & Dick Allen Diabetes Center — Newport Beach, California
- Artemis Institute for Clinical Research — San Diego, California
- Encompass Clinical Research — Spring Valley, California
- Diablo Clinical Research, Inc. — Walnut Creek, California
- Lynn Institute of Denver — Aurora, Colorado
- Bridgeport Hospital — Bridgeport, Connecticut
- Yale University School of Medicine — New Haven, Connecticut
- Encore Medical Research — Hollywood, Florida
- Suncoast Research Group — Miami, Florida
- Onhealth Research Center — Miami, Florida
- Precision Clinical Research — Sunrise, Florida
- Einstein Clinical Research — Vero Beach, Florida
- ClinCept Clinical Research - MH — Columbus, Georgia
- Northeast Georgia Medical Center — Gainesville, Georgia
- Pivotal Research Solutions — Stonecrest, Georgia
- East-West Medical Research Institute — Honolulu, Hawaii
- Northwestern University — Chicago, Illinois
- Integrated Clinical Trial Services, Inc. — West Des Moines, Iowa
- Pennington Biomedical Research Center — Baton Rouge, Louisiana
- Great Lakes Research Group, Inc. — Bay City, Michigan
- Great Lakes Research Institute — Southfield, Michigan
- StudyMetrix Research — City of Saint Peters, Missouri
- Las Vegas Endocrinology — Henderson, Nevada
- Albany Medical College, Division of Community Endocrinology — Albany, New York
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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Explore by condition: All Obesity clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.