Effect of Dupilumab on the Muscle Function of the Esophagus (food Pipe) in Participants with Eosinophilic Esophagitis (EoE) (NCT06665971)
Effect of Dupilumab on Esophageal Peristaltic Function in Participants with Eosinophilic Esophagitis
🩺 Plain-English Summary (8th-Grade Level)
The goal of this study is to research Dupilumab, an FDA approved medication in treating patients diagnosed with Eosinophilic esophagitis (EoE). The drug works by controlling allergic inflammation of the esophagus. The esophagus is a food pipe that transfers food from the mouth into the stomach. Participants with EoE have dysfunction of the muscle of the esophagus (impaired peristalsis) that is not favorable for the transport function. Main question this study aims to answer is: Whether Dupilumab helps improve muscle activity of the esophagus in participants with EOE? Participants will: Take Dupilumab every week for 12 weeks. Visit the clinic before and after starting the medication. Keep a diary of symptoms.
Who can join: Review the eligibility criteria below.
Location: University of California San Diego (UCSD) Health Medical center — La Jolla, California
Age range: 22 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of California San Diego (UCSD) Health Medical center — La Jolla, California
📞 Contact the Study Coordinator
Phone: (314) 685-9214
Email: ucsdgimotility@gmail.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Eosinophilic Esophagitis (EoE)
- A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care — Phoenix, Arizona
- Surface EMG Testing on Swallowing in EoE Patients — Rochester, Minnesota
- A Study to Investigate the Efficacy and Safety of NSI-8226 in Adults With Eosinophilic Esophagitis — Dothan, Alabama
- A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis — Phoenix, Arizona
- Esophageal String Test Monitoring to Monitor Eosinophilic Esophagitis During Oral Immunotherapy — Philadelphia, Pennsylvania
Explore by condition: All Eosinophilic Esophagitis (EoE) clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.