๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-04-17

A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM) (NCT06679101)

A Phase 3, Randomized, Open-label Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)

๐ŸŸข Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: GlaxoSmithKline

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this Phase 3 study is to evaluate if BRd prolongs progression free survival (PFS) and/or improves minimal residual disease (MRD) negative status compared with DRd in participants with TI-NDMM.

Who can join: Review the eligibility criteria below.

Location: GSK Investigational Site โ€” Mobile, Alabama

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (181 Sites)

Showing the first 25 of 181 sites.

  • GSK Investigational Site โ€” Mobile, Alabama
  • GSK Investigational Site โ€” Phoenix, Arizona
  • GSK Investigational Site โ€” Beverly Hills, California
  • GSK Investigational Site โ€” Pasadena, California
  • GSK Investigational Site โ€” Aurora, Colorado
  • GSK Investigational Site โ€” Washington D.C., District of Columbia
  • GSK Investigational Site โ€” Englewood, Florida
  • GSK Investigational Site โ€” Lady Lake, Florida
  • GSK Investigational Site โ€” Pembroke Pines, Florida
  • GSK Investigational Site โ€” Saint Augustine, Florida
  • GSK Investigational Site โ€” Atlanta, Georgia
  • GSK Investigational Site โ€” Portland, Maine
  • GSK Investigational Site โ€” Worcester, Massachusetts
  • GSK Investigational Site โ€” Ann Arbor, Michigan
  • GSK Investigational Site โ€” Detroit, Michigan
  • GSK Investigational Site โ€” Billings, Montana
  • GSK Investigational Site โ€” Hackensack, New Jersey
  • GSK Investigational Site โ€” New York, New York
  • GSK Investigational Site โ€” Stony Brook, New York
  • GSK Investigational Site โ€” Charlotte, North Carolina
  • GSK Investigational Site โ€” Winston-Salem, North Carolina
  • GSK Investigational Site โ€” Columbus, Ohio
  • GSK Investigational Site โ€” Providence, Rhode Island
  • GSK Investigational Site โ€” Austin, Texas
  • GSK Investigational Site โ€” Austin, Texas

๐Ÿ“ž Contact the Study Coordinator

Phone: (877) 379-3718

Email: GSKClinicalSupportHD@gsk.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Multiple Myeloma clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—