๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-05-11

A Trial of Eptinezumab in Participants With Migraine and Insufficient Response to Anti-CGRP Medications (NCT06701526)

Interventional, Open-label Trial, Investigating the Effectiveness of Eptinezumab in Participants With Migraine and Previous Inadequate Response to CGRP-targeting Therapies

๐Ÿ”ต Active, Not Recruiting Phase4 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: H. Lundbeck A/S

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The main goal of this trial is to learn whether eptinezumab improves migraine symptoms and quality of life of participants with migraine who did not perceive a sufficient improvement during previous treatment with therapies targeting calcitonin gene-related peptide (CGRP).

Who can join: Review the eligibility criteria below.

Location: Neuropain Medical Center โ€” Fresno, California

Age range: 18 Years to 75 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (28 Sites)

Showing the first 25 of 28 sites.

  • Neuropain Medical Center โ€” Fresno, California
  • Sunwise Clinical Research, LLC. โ€” Oakland, California
  • The Neuron Clinic โ€” San Marcos, California
  • St. Joseph's Hospital and Medical Center - Barrow Neurological Institute โ€” Aurora, Colorado
  • Advanced Neurology of Colorado, LLC โ€” Longmont, Colorado
  • Research of the Rockies โ€” Parker, Colorado
  • Hasbani & Hasbani MDs โ€” New Haven, Connecticut
  • New England Institute for Neurology and Headache โ€” Stamford, Connecticut
  • Brainstorm Research โ€” Miami, Florida
  • Premiere Research Institute at Palm Beach Neurology โ€” West Palm Beach, Florida
  • PANDA Neurology and Atlanta Headache Specialists โ€” Atlanta, Georgia
  • St Luke's Meridian Medical Center โ€” Meridian, Idaho
  • Chicago Headache Center & Research Institute โ€” Chicago, Illinois
  • Crescent City Headache and Neurology โ€” New Orleans, Louisiana
  • Neurology Center of New England P.C. โ€” Foxborough, Massachusetts
  • MedVadis Research Corporation โ€” Waltham, Massachusetts
  • Mass Institute of Clinical Research โ€” Westborough, Massachusetts
  • Memorial Healthcare โ€” Owosso, Michigan
  • Albany Medical College โ€” Albany, New York
  • Dent Neurosciences Research Center, Inc. โ€” Amherst, New York
  • North Suffolk Neurology โ€” Port Jefferson Station, New York
  • NeuroScience Research Center, LLC. โ€” Canton, Ohio
  • C7 Research โ€” Cleveland, Ohio
  • Thomas Jefferson University โ€” Philadelphia, Pennsylvania
  • Preferred Primary Care Physicians, Inc. โ€” Pittsburgh, Pennsylvania

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Migraine clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—