Noninvasive Brain Stimulation in Adult Amblyopia (NCT06712849)
Multi-day Effect of Noninvasive Brain Stimulation in Adults With Amblyopia
🩺 Plain-English Summary (8th-Grade Level)
The goal of this randomized controlled trial is to investigate the effectiveness of non-invasive brain stimulation in treating adults with amblyopia. The main questions it aims to answer are: 1. What are the effects of non-invasive brain stimulation on neuronal plasticity in the visual cortex of adults with amblyopia, and does it produce lasting changes? 2. Do cumulative sessions of non-invasive brain stimulation influence neural plasticity and higher-order visual functions in adults with amblyopia? The investigators hypothesize that non-invasive brain stimulation will show a positive cumulative effect after five (5) consecutive days of stimulation on visual perception and function in adults with amblyopia. Participants will be randomized into one of two treatment groups: 1. High-frequency transcranial random noise stimulation (hf-tRNS). 2. Sham stimulation. Researchers will compare baseline measurements of crowded visual acuity, contrast sensitivity, stereoacuity, phosphene thresholds, global motion perception, form pattern recognition and pattern-reversal visual evoked potentials (VEPs) to post-treatment measurements for each group.
Who can join: Review the eligibility criteria below.
Location: Midwestern University Eye Institute — Downers Grove, Illinois
Age range: 18 Years to 55 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Midwestern University Eye Institute — Downers Grove, Illinois
📞 Contact the Study Coordinator
Phone: (630) 960-3172
Email: achakr@midwestern.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Amblyopia
- Binocular iPad Sub-Study — Dallas, Texas
- Optical Correction and Visual Functions of Adults With Amblyopia — Waterloo, Ontario
- A Randomized Trial to Evaluate Sequential vs Simultaneous Patching — Birmingham, Alabama
- Amblyopia Treatment for Children Aged 8 to 12 Years — Dallas, Texas
- Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy — Cleveland, Ohio
Explore by condition: All Amblyopia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.