A Randomized Comparison of Personalized Therapy Mgmt Based On Coronary Atherosclerotic Plaque Vs. Usual Care for Symptomatic Patients With Suspicion of CAD (NCT06713239)
A Randomized Comparison of Personalized Management for Medical and Interventional Therapy Based On Coronary Atherosclerotic Plaque Versus Usual Care for Symptomatic Patients With Suspicion of CAD
🩺 Plain-English Summary (8th-Grade Level)
PARAMOUNT is a prospective randomized open-label trial testing the hypothesis that a personalized management strategy in symptomatic patients with suspicion of coronary artery disease (CAD), using a CT-based coronary atherosclerotic plaque assessment by AI-enabled quantitative software improves: certainty for diagnosis of CAD, control of CAD risk factors and efficiency of ICA referral with appropriate PCI compared to the usual care strategy based on current AHA/ACC guidelines for care of symptomatic patients with suspicion of CAD.
Who can join: Review the eligibility criteria below.
Location: Cardiology Associates of Mobile — Mobile, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (21 Sites)
- Cardiology Associates of Mobile — Mobile, Alabama
- Valiance Clinical Research- Huntington Park — Huntington Park, California
- Cardiovascular Institute of San Diego — San Diego, California
- Valiance Clinical Research- Tarzana — Tarzana, California
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center — Torrance, California
- Intermountain Health Saint Joseph Hospital — Broomfield, Colorado
- Tampa Cardiovascular Interventions and Research — Tampa, Florida
- Flourish Research — Winter Park, Florida
- Endeavor Health Clinical Operations — Evanston, Illinois
- MercyOne Des Moines Medical Center — West Des Moines, Iowa
- Saint Elizabeth Medical Center — Edgewood, Kentucky
- Tulane University — New Orleans, Louisiana
- Flourish- Bowie — Bowie, Maryland
- St. Louis Heart and Vascular — Bridgeton, Missouri
- Advanced Heart and Vascular Institute of Hunterdon — Flemington, New Jersey
- Capital Cardiology Associates — Albany, New York
- University of Cincinnatti — Cincinnati, Ohio
- Oklahoma Cardiovascular Research Group — Oklahoma City, Oklahoma
- The University of Tennessee Medical Center — Knoxville, Tennessee
- Medical City Fort Worth Hospital — Fort Worth, Texas
- Chippenham and Johnston Willis Hospitals — Richmond, Virginia
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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Explore by condition: All Coronary Artery Disease clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.