A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy (NCT06722157)
Randomized, Double-masked, Active-controlled, Multicenter Study to Evaluate Efficacy and Safety of Two Regimens of Intravitreal BI 771716 Against Pegcetacoplan in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration VERDANT Trial
🩺 Plain-English Summary (8th-Grade Level)
This study is open to people 50 years or older with an eye condition called geographic atrophy. The purpose of this study is to compare a medicine called BI 771716 with a medicine called pegcetacoplan. BI 771716 is being developed to treat people with geographic atrophy. Pegcetacoplan is a medicine already used to treat people with geographic atrophy. In this study, participants receive either BI 771716 or pegcetacoplan as injections in the eye. Participants are in the study for a little longer than a year and visit the study site every 4 weeks. At the visits, the study doctor checks the eyes of the participants. The results are compared between the groups of participants to see whether the treatment works. The study doctor also regularly checks participants' health and takes note of any unwanted effects.
Who can join: Review the eligibility criteria below.
Location: Associated Retina Consultants — Gilbert, Arizona
Age range: 50 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (46 Sites)
Showing the first 25 of 46 sites.
- Associated Retina Consultants — Gilbert, Arizona
- Associated Retina Consultants, Ltd. — Phoenix, Arizona
- Phoenix Retina Associates — Phoenix, Arizona
- Retina Macula Institute of Arizona — Scottsdale, Arizona
- Global Research Management — Glendale, California
- Retina Associates of Southern California — Huntington Beach, California
- Retinal Consultants Medical Group, Inc — Modesto, California
- Eye Research Foundation — Newport Beach, California
- Retina Consultants of San Diego — Poway, California
- Retinal Consultants Medical Group — Sacramento, California
- Bay Area Retina Associates - Walnut Creek — Walnut Creek, California
- Colorado Retina Associates — Lakewood, Colorado
- Connecticut Eye Consultants, PC — Danbury, Connecticut
- Retina Group of New England, PC — Waterford, Connecticut
- Rand Eye Institute — Deerfield Beach, Florida
- Retina Group of Florida — Fort Lauderdale, Florida
- Eye Associates of Pinellas — Pinellas Park, Florida
- Retina Vitreous Associates of Florida — St. Petersburg, Florida
- Southeast Retina Center, PC — Augusta, Georgia
- University Retina and Macula Associates — Lemont, Illinois
- Illinois Retina Associates - Oak Park — Oak Park, Illinois
- Butchertown Clinical Trials — Louisville, Kentucky
- Mid Atlantic Retina Specialists — Hagerstown, Maryland
- Ophthalmic Consultants of Boston — Boston, Massachusetts
- Retina Consultants of Minnesota — Edina, Minnesota
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
Explore by condition: All Macular Degeneration, Age-related clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.