Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC (NCT06726161)
Phase 1/2 Randomized, Controlled, Open-label Trial of Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ Unresectable Hepatocellular Carcinoma (HCC)
๐ฉบ Plain-English Summary (8th-Grade Level)
Phase 1/2 randomized, controlled, open-label trial of theranostic pair RYZ811 (diagnostic) and RYZ801 (therapeutic) to identify and treat subjects with GPC3+ unresectable hepatocellular carcinoma (HCC)
Who can join: Review the eligibility criteria below.
Location: Research Facility โ Birmingham, Alabama
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (13 Sites)
- Research Facility โ Birmingham, Alabama
- Research Facility โ Phoenix, Arizona
- Research Facility โ Tucson, Arizona
- Research Facility โ Orange, California
- Research Facility โ Jacksonville, Florida
- Research Facility โ Lexington, Kentucky
- Research Facility โ Baltimore, Maryland
- Research Facility โ Rochester, Minnesota
- Research Facility โ Omaha, Nebraska
- Research Facility โ New York, New York
- Research Facility โ Houston, Texas
- Research Facility โ Charlottesville, Virginia
- Research Facility โ Seattle, Washington
๐ Contact the Study Coordinator
Phone: (619) 657-0057
Email: clinicaltrials@rayzebio.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Hepatocellular Carcinoma (HCC)
- Streamlined Resin Y90 Radiation Segmentectomy for Small HCC โ Chapel Hill, North Carolina
- A US Study to Evaluate Transarterial Radioembolization (TARE) in Combination With Durvalumab and Bevacizumab Therapy in People With Unresectable Hepatocellular Carcinoma Amenable to TARE โ Aurora, Colorado
- Utilize Imaging to Assess Changes in Hepatocellular Carcinoma Perfusion as Potentiated by Intra-Arterial Nitroglycerin โ San Francisco, California
- Radiation Therapy Followed by Durvalumab (MEDI4736) and Tremelimumab And Surgery Versus Radiation Therapy Followed by Surgery for Resectable Hepatocellular Carcinoma. โ Hamilton, Ontario
- Using Radiotherapy and Immunotherapy to Treat Advanced Liver Cancer Before Transplant โ London, Ontario
- Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y90 โ Palo Alto, California
Explore by condition: All Hepatocellular Carcinoma (HCC) clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.