MTOR Inhibitors in Older Adults (NCT06727305)
Characterization of mTOR Inhibitor Pharmacokinetics and Pharmacodynamics in Older Adults .
๐ฉบ Plain-English Summary (8th-Grade Level)
Over the past decades, healthcare systems face significant challenges to meet the needs of an aging population due to progressive debility, functional decline and chronic diseases development. While there is a growing appreciation of the potential impact of mTOR inhibitors on slowing aging processes, preventing chronic disease and prolonging healthy lifespan, a major challenge in developing clinical trials to establish the clinical efficacy of mTOR inhibitors is the absence of pharmacokinetics (PK) and pharmacodynamics (PD) data in older adults. The proposed study will provide the foundation for future clinical trials assessing the role of mTOR inhibitors on aging related indications
Who can join: Review the eligibility criteria below.
Location: UT Southwestern Medical Center โ Dallas, Texas
Age range: 65 Years to 80 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (1 Sites)
- UT Southwestern Medical Center โ Dallas, Texas
๐ Contact the Study Coordinator
Phone: (216) 334-7534
Email: Irina.Timofte@utsouthwestern.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Aging
- A Pilot Study on Reverse Aging (The REVERSE Study) โ Cincinnati, Ohio
- Feasibility of Home-based tES for Older Adults at Risk of Falling โ Roslindale, Massachusetts
- Heat, Microvascular Function and Aging โ Milwaukee, Wisconsin
- Protein Quantity and Quality in Older Subjects โ Hamilton, Ontario
- Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction During Disuse โ Salt Lake City, Utah
- Effect of a Daily Supplement on Plasma PAI-1 Levels โ Los Angeles, California
Explore by condition: All Aging clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.