๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-30

Multicenter ALS Imaging Study (NCT06735014)

Multicenter Longitudinal Imaging in ALS for Disease Biomarker Development

๐ŸŸข Recruiting Interventional Protocol ๐Ÿ“Š Observational Clinical Research Sponsor: University of Minnesota

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a multi-site study of ALS participants and healthy controls who will undergo brain and cervical spine MRIs and NfL blood testing at up-to 4 time points over the course of a year. The primary goal is to identify objective biomarkers of disease progression that are biologically relevant, linearly progressive, and sensitive to change.

Who can join: Review the eligibility criteria below.

Location: University of Florida โ€” Gainesville, Florida

Age range: 18 Years

๐Ÿงช Interventions in This Study

  • Magnetic Resonance Imaging (DIAGNOSTIC_TEST)
  • Plasma neurofilament light chain (NfL) quantification (DIAGNOSTIC_TEST)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (3 Sites)

  • University of Florida โ€” Gainesville, Florida
  • Northwestern University โ€” Evanston, Illinois
  • University of Minnesota โ€” Minneapolis, Minnesota

๐Ÿ“ž Contact the Study Coordinator

Phone: (612) 624-4911

Email: baile807@umn.edu

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—