๐๏ธ Verified NIH Record โข Updated 2026-08-14
A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With SCLC (NCT06745323)
A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With Small Cell Lung Cancer (SCLC) (DeLLphi-309)
๐ต Active, Not Recruiting Phase2 ๐ Investigational Drug / Biologic Sponsor: Amgen
๐ฉบ Plain-English Summary (8th-Grade Level)
The primary objective of this study is to describe the antitumor activity of tarlatamab in participants with small cell lung cancer (SCLC).
Who can join: Review the eligibility criteria below.
Location: University of California Los Angeles โ Los Angeles, California
Age range: 18 Years to 99 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (78 Sites)
Showing the first 25 of 78 sites.
- University of California Los Angeles โ Los Angeles, California
- Hartford HealthCare Cancer Institute at The Hospital of Central Connecticut โ Plainville, Connecticut
- AdventHealth Hematology and Oncology โ Orlando, Florida
- City of Hope Chicago โ Rockford, Illinois
- Health Partners Cancer Center at Regions Hospital โ Saint Paul, Minnesota
- New York Oncology Hematology PC โ Albany, New York
- Duke University โ Durham, North Carolina
- FirstHealth Cancer Center โ Pinehurst, North Carolina
- Guthrie Medical Group โ Sayre, Pennsylvania
- Tennessee Oncology PLLC - Chattanooga โ Chattanooga, Tennessee
- Tennessee Oncology, PLLC โ Nashville, Tennessee
- Virginia Cancer Specialists PC โ Fairfax, Virginia
- Fundacion Respirar โ Ciudad Autonoma de Buenos Aires, Buenos Aires
- Instituto de Investigaciones clinicas de Mar del Plata โ Mar del Plata, Buenos Aires
- Monash Medical Centre โ Clayton, Victoria
- Austin Health, Austin Hospital โ Heidelberg, Victoria
- Grand Hopital de Charleroi - Site des Viviers โ Charleroi,
- Universitair Ziekenhuis Antwerpen โ Edegem,
- Jessa Ziekenhuis - Campus Virga Jesse โ Hasselt,
- Liga Norte-Riograndense Contra O Cancer โ Natal, Rio Grande do Norte
- Hospital de Clinicas de Porto Alegre โ Porto Alegre, Rio Grande do Sul
- Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul โ Porto Alegre, Rio Grande do Sul
- Cipo - Centro Integrado de Pesquisa em Oncologia โ Porto Alegre, Rio Grande do Sul
- Hospital de Amor โ Barretos, Sรฃo Paulo
- Hospital de Base de Sao Jose do Rio Preto โ Sรฃo Josรฉ do Rio Preto, Sรฃo Paulo
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Small Cell Lung Cancer (SCLC)
- Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer โ Mobile, Alabama
- Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer โ Fayetteville, Arkansas
- Adjuvant Chemotherapy and Immunotherapy for Completely Resected Small Cell Lung Cancer โ Chicago, Illinois
- A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study) โ Duarte, California
- DAREON ยฎ -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy โ Mobile, Alabama
Explore by condition: All Small Cell Lung Cancer (SCLC) clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.