๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-14

A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With SCLC (NCT06745323)

A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With Small Cell Lung Cancer (SCLC) (DeLLphi-309)

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Amgen

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The primary objective of this study is to describe the antitumor activity of tarlatamab in participants with small cell lung cancer (SCLC).

Who can join: Review the eligibility criteria below.

Location: University of California Los Angeles โ€” Los Angeles, California

Age range: 18 Years to 99 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (78 Sites)

Showing the first 25 of 78 sites.

  • University of California Los Angeles โ€” Los Angeles, California
  • Hartford HealthCare Cancer Institute at The Hospital of Central Connecticut โ€” Plainville, Connecticut
  • AdventHealth Hematology and Oncology โ€” Orlando, Florida
  • City of Hope Chicago โ€” Rockford, Illinois
  • Health Partners Cancer Center at Regions Hospital โ€” Saint Paul, Minnesota
  • New York Oncology Hematology PC โ€” Albany, New York
  • Duke University โ€” Durham, North Carolina
  • FirstHealth Cancer Center โ€” Pinehurst, North Carolina
  • Guthrie Medical Group โ€” Sayre, Pennsylvania
  • Tennessee Oncology PLLC - Chattanooga โ€” Chattanooga, Tennessee
  • Tennessee Oncology, PLLC โ€” Nashville, Tennessee
  • Virginia Cancer Specialists PC โ€” Fairfax, Virginia
  • Fundacion Respirar โ€” Ciudad Autonoma de Buenos Aires, Buenos Aires
  • Instituto de Investigaciones clinicas de Mar del Plata โ€” Mar del Plata, Buenos Aires
  • Monash Medical Centre โ€” Clayton, Victoria
  • Austin Health, Austin Hospital โ€” Heidelberg, Victoria
  • Grand Hopital de Charleroi - Site des Viviers โ€” Charleroi,
  • Universitair Ziekenhuis Antwerpen โ€” Edegem,
  • Jessa Ziekenhuis - Campus Virga Jesse โ€” Hasselt,
  • Liga Norte-Riograndense Contra O Cancer โ€” Natal, Rio Grande do Norte
  • Hospital de Clinicas de Porto Alegre โ€” Porto Alegre, Rio Grande do Sul
  • Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul โ€” Porto Alegre, Rio Grande do Sul
  • Cipo - Centro Integrado de Pesquisa em Oncologia โ€” Porto Alegre, Rio Grande do Sul
  • Hospital de Amor โ€” Barretos, Sรฃo Paulo
  • Hospital de Base de Sao Jose do Rio Preto โ€” Sรฃo Josรฉ do Rio Preto, Sรฃo Paulo

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—